Les tutelles
CNRS-MNHN
Elisabeth MOURAY
Entité de rattachement
PPL Parasites et Protistes Libres
Thème interdisciplinaire de recherche
Plasmodium falciparum et Trypanosoma brucei
Spécialité
Biologie moléculaire et cellulaire, biochimie des protéines, synthèse de protéines recombinantes, cultures cellulaires
Contact
Téléphone
01 40 79 35 16
Adresse(s)
61 rue Buffon (CP52)
75005 Paris
Responsabilités dans l'unité
- Assistante de prévention
- Personne compétente en Radioprotection
- Responsable pièce de cultures cellulaires
Activités de recherche
- Etude des kinésines de Trypanosoma brucei
- Etude des enzymes intervenant dans les mécanismes de prénylation chez T. brucei et chez Plasmodium falciparum
- Tests d'inhibition de Plasmodium falciparum et de Trypanosoma brucei in vitro
Publications
2022
- 2022 — Biodereplication of antiplasmodial extracts: application to the Amazonian medicinal plant Piper coruscans Kunth. Molecules 2022, 27(21), 7638.,
2021
- 2021 — Targeted Isolation of Hemitheion from Mostuea brunonis, A Proposed Biosynthetic Intermediate of Theionbrunonines. Journal of Natural Products 23;84(4):1409-1413.,
2020
- Mars 2020 — Eumitrins C-E: Structurally diverse xanthone dimers from the vietnamese lichen Usnea baileyi. Fitoterapia. Vol. 141, p. 104449.,ISSN:0367326X
- 2020 — Secondary Metabolites from the Culture of the Marine-derived Fungus Paradendryphiella salina PC 362H and Evaluation of the Anticancer Activity of Its Metabolite Hyalodendrin. Mar Drugs. Apr 3;18(4):191.,
- 2020 — Synthesis of novel G factor- or chloroquine-artemisinin hybrids and conjugates with polyamines with potent antiplasmodial activity. ACS Med Chem Lett, 11(5):921-927.,
- 2020 — Molecular Networking Reveals Serpentinine-related Bisindole Alkaloids from the “Good Old” Picralima nitida.. J. Nat. Prod. 83:1207-12016.,
- 2020 — Streamlined Targeting of Amaryllidaceae Alkaloids From The Bulbs of Crinum scillifolium Using Spectrometric and Taxonomically-Informed Scoring Metabolite Annotations. Phytochemistry, 179:112485.,
- 2020 — Synthesis and Antiplasmodial Activity of Novel Fosmidomycin Derivatives and Conjugates with Artemisinin and Aminochloroquinoline. Molecules 25(20):4858.,
2018
- Octobre 2018 — Theionbrunonines A and B: Dimeric Vobasine Alkaloids Tethered by a Thioether Bridge from Mostuea brunonis. Organic Letters. Vol. 20, n° 20, p. 6596-6600.,ISSN:1523-7060, 1523-7052
2017
- Décembre 2017 — Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo. Malaria Journal. Vol. 16, n° 1.,ISSN:1475-2875