Entité de rattachement
PPL Parasites et Protistes Libres
Thème interdisciplinaire de recherche
Plasmodium falciparum et Trypanosoma brucei
Spécialité
Biologie moléculaire et cellulaire, biochimie des protéines, synthèse de protéines recombinantes, cultures cellulaires

Contact

Réseaux sociaux
Courriel
elisabeth.mouray [at] mnhn.fr
mouray [at] mnhn.fr
Téléphone
01 40 79 35 16
Adresse(s)

61 rue Buffon (CP52)
75005 Paris

Responsabilités dans l'unité

  • Assistante de prévention
  • Personne compétente en Radioprotection
  • Responsable pièce de cultures cellulaires

Présentation

Activités de recherche
  • Etude des kinésines de Trypanosoma brucei
  • Etude des enzymes intervenant dans les mécanismes de prénylation chez T. brucei et chez Plasmodium falciparum
  • Tests d’inhibition de Plasmodium falciparum et de Trypanosoma brucei in vitro
Trypanosoma brucei © E. Mouray & L. Kohl

Trypanosoma brucei, phase contrast image (Nucleus and kinetoplast in mauve, Kinesin labelling in green) © E. Mouray & L. Kohl

Publications

2024
  • Vamvoukaki G, Antoniou AI, Baltas M, Mouray E, Charneau S, Grellier P, Athanassopoulos CM, 2024 — Synthesis of Novel Artemisinin, Ciprofloxacin, and Norfloxacin Hybrids with Potent Antiplasmodial Activity. Antibiotics (Basel). 13(2):142 , ,
    https://dx.doi.org/doi: 10.3390/antibiotics13020142
2023
  • Otogo N'Nang E, Cauchie G, Retailleau P, Agnandji ST, Gallard JF, Mouray E, Grellier P, Champy P, Le Pogam P, Beniddir MA, 2023 — From the Spectroscopic Reassessment of Authentic Alkaloid Samples to the Molecular Networking-Guided Discovery of Criophylline-Related Analogues from Callichilia inaequalis. J Nat Prod . 2023 May 26;86(5):1202-1210 , ,
    https://dx.doi.org/10.1021/acs.jnatprod.2c01084
2022
  • Vásquez-Ocmín PG, Gallard J-F, Van Baelen A-C, Leblanc K, Cojean S, Mouray E, Grellier P, Amasifuén C, Beniddir M, Evanno L, Figadère B, Maciuk A. , 2022 — Biodereplication of antiplasmodial extracts: application to the Amazonian medicinal plant Piper coruscans Kunth. Molecules 2022, 27(21), 7638 , ,
    https://dx.doi.org/3390/molecules27217638
2021
  • Otogo N'Nang E, Le Pogam P, Ndong Mba T, Sima Obiang C, Mouray E, Grellier P, Kumulungui B, Champy P, Beniddir M, 2021 — Targeted Isolation of Hemitheion from Mostuea brunonis, A Proposed Biosynthetic Intermediate of Theionbrunonines. Journal of Natural Products 23;84(4):1409-1413 , ,
    https://dx.doi.org/d.1c00143.
2020
  • Nguyen Van-Kieu, Genta-Jouve Grégory, Duong Thuc-Huy, Beniddir Mehdi A., Gallard Jean-François, Ferron Solenn, Boustie Joël, Mouray Elisabeth, Grellier Philippe, Chavasiri Warinthorn & Le Pogam Pierre, mars 2020 — Eumitrins C-E: Structurally diverse xanthone dimers from the vietnamese lichen Usnea baileyi. Fitoterapia vol. 141, , p. 104449
    ISSN
    0367326X
    https://dx.doi.org/10.1016/j.fitote.2019.104449
  • Alcover CF, Bernadat G, Kabran FA, Le Pogam P, Evanno L, Leblanc K, Fox Ramos AE, Gallard J-F, Mouray E, Grellier P, Poupon E, Beniddir MA. , 2020 — Molecular Networking Reveals Serpentinine-related Bisindole Alkaloids from the “Good Old” Picralima nitida.. J. Nat. Prod. 83:1207-12016 , ,
    https://dx.doi.org/d.9b01247
  • Dezaire A, Marchand CH, Vallet M, Ferrand N, Chaouch S, Mouray E, Larsen AK, Sabbah M, Lemaire SD, Prado S, Escargueil AE. , 2020 — Secondary Metabolites from the Culture of the Marine-derived Fungus Paradendryphiella salina PC 362H and Evaluation of the Anticancer Activity of Its Metabolite Hyalodendrin. Mar Drugs. Apr 3;18(4):191 , ,
    https://dx.doi.org/8040191
  • N’Tamon AD, Okpekon AT, Bony NF, Bernadat G, Gallard J-F, Kouamé T, Séon-Méniel B, Leblanc K, Rharrahbti S, Mouray E, Grellier P, Ake M, Amin NC, Champy P, Beniddir MA, Le Pogam P., 2020 — Streamlined Targeting of Amaryllidaceae Alkaloids From The Bulbs of Crinum scillifolium Using Spectrometric and Taxonomically-Informed Scoring Metabolite Annotations. Phytochemistry, 179:112485 , ,
    https://dx.doi.org/.2020.112485
  • Palla D, Antoniou AI, Baltas M, Menendez C, Grellier P, Mouray E, Athanassopoulos CM. , 2020 — Synthesis and Antiplasmodial Activity of Novel Fosmidomycin Derivatives and Conjugates with Artemisinin and Aminochloroquinoline. Molecules 25(20):4858 , ,
    https://dx.doi.org/204858
  • Pepe DA, Toumpa D, André-Barrès C, Menendez C, Mouray E, Baltas M, Grellier P, Papaioannou D, Athanassopoulos CM, 2020 — Synthesis of novel G factor- or chloroquine-artemisinin hybrids and conjugates with polyamines with potent antiplasmodial activity. ACS Med Chem Lett, 11(5):921-927 , ,
    https://dx.doi.org/10.1021/acsmedchemlett.9b00669
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