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Molécules de Communication et Adaptation des Micro-organismes (MCAM)
UMR 7245

List of publications

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Klaubert Tim J., Gellner Jonas, Bernard Charles, Effert Juliana, Lombard Carine, Kaila Ville R. I., Bode Helge B., Li Yanyan & Groll Michael, 2025 — Molecular basis for azetidine-2-carboxylic acid biosynthesis. Nature Communications vol. 16, n° 1, p. 1348
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-025-56610-6
Boudrioua Abdelhakim, Baëtz Benjamin, Desmadril Solenn, Goulard Christophe, Groo Anne-Claire, Lombard Carine, Gueulle Sabrina, Marugan Marie, Malzert-Fréon Aurélie, Hartke Axel, Li Yanyan & Giraud Caroline, 2025 — Lasso peptides sviceucin and siamycin I have anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant pathogens. iScience , , p. 111922
ISSN
2589-0042
https://dx.doi.org/10.1016/j.isci.2025.111922
Schiefelbein Kevin, Lang Jakob, Schuster Matthias, Grigglestone Claire E., Striga Robin, Bigler Laurent, Schuman Meredith C., Zerbe Oliver, Li Yanyan & Hartrampf Nina, 2024 — Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides. Journal of the American Chemical Society vol. 146, n° 25, p. 17261-17269
ISSN
0002-7863
https://dx.doi.org/10.1021/jacs.4c03898
Leprevost Laura, Jünger Sophie, Lippens Guy, Guillaume Céline, Sicoli Giuseppe, Oliveira Lydie, Falcone Enrico, de Santis Emiliano, Rivera-Millot Alex, Billon Gabriel, Stellato Francesco, Henry Céline, Antoine Rudy, Zirah Séverine, Dubiley Svetlana et al., 2024 — A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to metal stress. Proceedings of the National Academy of Sciences vol. 121, n° 49, e2408304121
https://dx.doi.org/10.1073/pnas.2408304121
Baquero Fernando, Beis Konstantinos, Craik David J., Li Yanyan, Link A. James, Rebuffat Sylvie, Salomón Raúl, Severinov Konstantin, Zirah Séverine & Hegemann Julian D., 2024 — The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide. Natural Product Reports vol. 121, , e2408304121
ISSN
1460-4752
https://dx.doi.org/10.1039/D3NP00046J
Effert Juliana, Westphalen Margaretha, Calderari Andrea, Shi Yi-Ming, Elamri Isam, Najah Soumaya, Grün Peter, Li Yanyan, Gruez Arnaud, Weissman Kira J. & Bode Helge B, 2024 — Pyrrolizwilline, a unique bacterial alkaloid assembled by a nonribosomal peptide synthetase and non-enzymatic dimerization. Angewandte Chemie International Edition vol. 63, , e202411258
ISSN
1521-3773
https://dx.doi.org/10.1002/anie.202411258
Bernard Charles, Li Yanyan, Lopez Philippe & Bapteste Eric, 2023 — Large-Scale Identification of Known and Novel RRNPP Quorum-Sensing Systems by RRNPP_Detector Captures Novel Features of Bacterial, Plasmidic, and Viral Coevolution. Molecular Biology and Evolution vol. 40, n° 4, msad062
ISSN
1537-1719
https://dx.doi.org/10.1093/molbev/msad062
Aggarwal Shifu, Huang Elaine, Do Hackwon, Makthal Nishanth, Li Yanyan, Bapteste Eric, Lopez Philippe, Bernard Charles & Kumaraswami Muthiah, 2023 — The leaderless communication peptide (LCP) class of quorum-sensing peptides is broadly distributed among Firmicutes. Nature Communications vol. 14, n° 1, p. 5947
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-023-41719-3
Rivas Arenas Laura A., de Paiva Fernanda C. R., de O. Rossini Nicolas, Li YanYan, Spencer Jonathan, Leadlay Peter & Dias Marcio V. B., 2022 — Crystal structure of BtrK, a decarboxylase involved in the (S)-4-amino-2-hydroxybutyrate (AHBA) formation during butirosin biosynthesis. Journal of Molecular Structure vol. 1267, , p. 133576
ISSN
0022-2860
https://dx.doi.org/10.1016/j.molstruc.2022.133576
Madi-Moussa Désiré, Deracinois Barbara, Teiar Radja, Li Yanyan, Mihasan Marius, Flahaut Christophe, Rebuffat Sylvie, Coucheney Françoise & Drider Djamel, 2022 — Structure of Lacticaseicin 30 and Its Engineered Variants Revealed an Interplay between the N-Terminal and C-Terminal Regions in the Activity against Gram-Negative Bacteria. Pharmaceutics vol. 14, n° 9, p. 1921
ISSN
1999-4923
https://dx.doi.org/10.3390/pharmaceutics14091921
Bernard Charles, Li Yanyan, Lopez Philippe & Bapteste Eric, 2021 — Beyond arbitrium: identification of a second communication system in Bacillus phage phi3T that may regulate host defense mechanisms. The ISME Journal vol. 15, , p. 545-549
ISSN
1751-7370
https://dx.doi.org/10.1038/s41396-020-00795-9
Miethke Marcus, Pieroni Marco, Weber Tilmann, Brönstrup Mark, Hammann Peter, Halby Ludovic, Arimondo Paola B., Glaser Philippe, Aigle Bertrand, Bode Helge B., Moreira Rui, Li Yanyan, Luzhetskyy Andriy, Medema Marnix H., Pernodet Jean-Luc et al., 2021 — Towards the sustainable discovery and development of new antibiotics. Nature Reviews Chemistry vol. 5, , p. 726-749
ISSN
2397-3358
https://dx.doi.org/10.1038/s41570-021-00313-1
Boudrioua Abdelhakim, Li Yanyan, Hartke Axel & Giraud Caroline, April 2020 — Opposite effect of vancomycin and D-Cycloserine combination in both vancomycin resistant Staphylococcus aureus and enterococci. FEMS microbiology letters vol. 367, n° 8,
ISSN
1574-6968
https://dx.doi.org/10.1093/femsle/fnaa062
Bernard Charles, Lannes Romain, Li Yanyan, Bapteste Éric & Lopez Philippe, 2020 — Rich Repertoire of Quorum Sensing Protein Coding Sequences in CPR and DPANN Associated with Interspecies and Interkingdom Communication. mSystems vol. 5, n° 5, e00414--20
ISSN
2379-5077
https://dx.doi.org/10.1128/mSystems.00414-20
Sayous Victor, Lubrano Paul, Li Yanyan & Acevedo-Rocha Carlos G., 2020 — Unbiased libraries in protein directed evolution. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics vol. 1868, n° 2, p. 140321
ISSN
1570-9639
https://dx.doi.org/10.1016/j.bbapap.2019.140321
Li Yanyan & Rebuffat Sylvie, 2020 — The manifold roles of microbial ribosomal peptide-based natural products in physiology and ecology. The Journal of Biological Chemistry vol. 295, n° 1, p. 34-54
ISSN
1083-351X
https://dx.doi.org/10.1074/jbc.REV119.006545
Hong Zhilai, Bolard Arnaud, Giraud Caroline, Prévost Sébastien, Genta-Jouve Grégory, Deregnaucourt Christiane, Häussler Susanne, Jeannot Katy & Li Yanyan, 2019 — Azetidine-Containing Alkaloids Produced by a Quorum-Sensing Regulated Nonribosomal Peptide Synthetase Pathway in Pseudomonas aeruginosa. Angewandte Chemie International Edition vol. 58, n° 10, p. 3178-3182
ISSN
14337851
https://dx.doi.org/10.1002/anie.201809981
Cheibas Cristina, Cordier Marie, Li Yanyan & Kaïm Laurent El, 2019 — A Ugi Straightforward Access to Bis-β-lactam Derivatives. European Journal of Organic Chemistry vol. 2019, n° 27, p. 4457-4463
ISSN
1099-0690
https://dx.doi.org/10.1002/ejoc.201900678
Mevaere Jimmy, Goulard Christophe, Schneider Olha, Sekurova Olga N., Ma Haiyan, Zirah Séverine, Afonso Carlos, Rebuffat Sylvie, Zotchev Sergey B. & Li Yanyan, 2018 — An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts. Scientific Reports vol. 8, n° 1, p. 8232
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-018-26620-0
Fu C., Auerbach D., Li Y., Scheid U., Luxenburger E., Garcia R., Irschik H. & Muller R., February 2017 — Solving the Puzzle of One-Carbon Loss in Ripostatin Biosynthesis. Angew Chem Int Ed Engl vol. 56, n° 8, p. 2192-2197
ISSN
1521-3773 (Electronic) 1433-7851 (Linking)
https://dx.doi.org/10.1002/anie.201609950
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