Affiliation entity
PPL Parasites and Free-living Protists
Interdisplinary research theme
Plasmodium berghei , rodent parasite
Speciality
Genetics / Parasitology

Contact

E-mail
delphine.depoix [at] mnhn.fr
Phone
01 40 79 35 11
Address(es)

61 rue Buffon (CP52)
75005 Paris

Responsibilities inside unit

  • Elected member of the Unit MCAM Council (2009-2019)

Responsibilities outside unit

 

Collections

In charge of the collection Unicellular Eukaryotes (parasitic protists), from June 2015

Teaching

Enseignements en master 1 et 2 (MNHN, UPMC, Université Tours) : Parasitologie, Mutualisme, outils moléculaires, Protistes, Babesiose et maladie de Lyme

Encadrement d’étudiants: IUT, licence, master

Presentation

Research Activities

I am interested in male gametogenesis of Plasmodium and more specifically in the formation and assembly of the flagellum of male gametes. By an appraoch combing functional genomics to cell biology, I aim to identify and characterise key actors in this essential step of the parasite life cycle. My model organism is the parasite Plasmodium berghei , the rodent model.

 

Gamétocytes mâle (rose) et femelle (bleu) de Plasmodium berghei © MNHN-Delphine Depoix

Gamétocytes mâle (rose) et femelle (bleu) de Plasmodium berghei © MNHN-Delphine Depoix

Credits
© MNHN-Delphine Depoix

Publications

2021
  • Garcia CHS, Depoix D, Carvalho PC, Bastos IMD, Ricart CAO, de Sousa MV, Ferguson DJP, Santana JM, Grellier P, Charneau S. J , 2021 — Comparative proteomic analysis of kinesin-8B deficient Plasmodium berghei during gametogenesis. J. Proteomics. 236:104118. , ,
    https://dx.doi.org/1.104118
2020
  • Depoix Delphine, Marques Sara Rute, Ferguson David JP, Chaouch Soraya, Duguet Thomas, Sinden Robert E, Grellier Philippe & Kohl Linda, 2020 — Vital role for Plasmodium berghei Kinesin8B in axoneme assembly during male gamete formation and mosquito transmission. Cell Microbiol. 22:e13121 , ,
    https://dx.doi.org/ https://doi.org/10.1111/cmi.13121
2018
  • Garcia Carlos H.S., Depoix Delphine, Queiroz Rayner M.L., Souza Jaques M.F., Fontes Wagner, de Sousa Marcelo V., Santos Marlon D.M., Carvalho Paulo C., Grellier Philippe & Charneau Sébastien, May 2018 — Dynamic molecular events associated to Plasmodium berghei gametogenesis through proteomic approach. Journal of Proteomics vol. 180, , p. 88-98
    ISSN
    18743919
    https://dx.doi.org/10.1016/j.jprot.2017.11.009
2013
  • Cornillot Emmanuel, Dassouli Amina, Garg Aprajita, Pachikara Niseema, Randazzo Sylvie, Depoix Delphine, Carcy Bernard, Delbecq Stéphane, Frutos Roger, Silva Joana C., Sutton Richard, Krause Peter J. & Mamoun Choukri Ben, 2013 — Whole genome mapping and re-organization of the nuclear and mitochondrial genomes of Babesia microti isolates. PLoS ONE vol. 8, n° 9, e72657
    ISSN
    1932-6203
    https://dx.doi.org/10.1371/journal.pone.0072657
2011
  • Spelman Kevin, Depoix Delphine, McCray Megan, Mouray Elisabeth & Grellier Philippe, July 2011 — The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo antimalarial activity. Phytother Res vol. 25, n° 7, p. 1098-1101
    ISSN
    1099-1573
    https://dx.doi.org/10.1002/ptr.3395
See all publications