Christophe GOULARD

Christophe GOULARD
Engineer
Affiliated entity
BIM Biochemistry of Microbial Interactions
Interdisciplinary research theme
Biochemistry
Speciality
Antimicrobial peptides, Microcines, Lasso peptides, HPLC, Mass spectrometry

Contact

Phone
01 40 79 48 98
Address(es)

63 rue Buffon
75005 Paris

Research activities

Production, purification and biochemical and physicochemical characterization of peptides and proteins, in particular antimicrobial peptides of bacteria.

Publications

2018
  • Mevaere Jimmy, Goulard Christophe, Schneider Olha, Sekurova Olga N., Ma Haiyan, Zirah Séverine, Afonso Carlos, Rebuffat Sylvie, Zotchev Sergey B. & Li Yanyan, 2018 — An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts. Scientific Reports. Vol. 8, n° 1, p. 8232.
    ISSN: 
    2045-2322
    https://dx.doi.org/10.1038/s41598-018-26620-0
  • Riera Elisabeth, Lamy Dominique, Goulard Christophe, Francour Patrice & Hubas Cédric, 2018 — Biofilm monitoring as a tool to assess the efficiency of artificial reefs as substrates: Toward 3D printed reefs. Ecological Engineering. Vol. 120, p. 230-237.
    ISSN: 
    09258574
    https://dx.doi.org/10.1016/j.ecoleng.2018.06.005
2017
  • Besse A., Vandervennet M., Goulard C., Peduzzi J., Isaac S., Rebuffat S. & Carre-Mlouka A., May 2017 — Halocin C8: an antimicrobial peptide distributed among four halophilic archaeal genera: Natrinema, Haloterrigena, Haloferax, and Halobacterium. Extremophiles : life under extreme conditions. Vol. 21, n° 3, p. 623-638.
    ISSN: 
    1433-4909 (Electronic) 1431-0651 (Linking)
    https://dx.doi.org/10.1007/s00792-017-0931-5
2016
  • Petit Vanessa W., Rolland Jean-Luc, Blond Alain, Cazevieille Chantal, Djediat Chakib, Peduzzi Jean, Goulard Christophe, Bachère Evelyne, Dupont Joëlle, Destoumieux-Garzón Delphine & Rebuffat Sylvie, March 2016 — A hemocyanin-derived antimicrobial peptide from the penaeid shrimp adopts an alpha-helical structure that specifically permeabilizes fungal membranes. Biochimica et Biophysica Acta (BBA) - General Subjects. Vol. 1860, n° 3, p. 557-568.
    ISSN: 
    03044165
    https://dx.doi.org/10.1016/j.bbagen.2015.12.010
2015
  • Li Yanyan, Ducasse Rémi, Zirah Séverine, Blond Alain, Goulard Christophe, Lescop Ewen, Giraud Caroline, Hartke Axel, Guittet Eric, Pernodet Jean-Luc & Rebuffat Sylvie, November 2015 — Characterization of Sviceucin from Streptomyces Provides Insight into Enzyme Exchangeability and Disulfide Bond Formation in Lasso Peptides. ACS Chemical Biology. Vol. 10, n° 11, p. 2641-2649.
    ISSN: 
    1554-8929, 1554-8937
    https://dx.doi.org/10.1021/acschembio.5b00584
2014
  • Mathavan I., Zirah S., Mehmood S., Choudhury H. G., Goulard C., Li Y., Robinson C. V., Rebuffat S. & Beis K., May 2014 — Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides. Nature chemical biology. Vol. 10, n° 5, p. 340-2.
    ISSN: 
    1552-4469 (Electronic) 1552-4450 (Linking)
    https://dx.doi.org/10.1038/nchembio.1499
2012
  • Yan K. P., Li Y., Zirah S., Goulard C., Knappe T. A., Marahiel M. A. & Rebuffat S., May 2012 — Dissecting the maturation steps of the lasso peptide microcin J25 in vitro. Chembiochem : a European journal of chemical biology. Vol. 13, n° 7, p. 1046-52.
    ISSN: 
    1439-7633 (Electronic) 1439-4227 (Linking)
    https://dx.doi.org/10.1002/cbic.201200016
  • Ducasse Rémi, Yan Kok-Phen, Goulard Christophe, Blond Alain, Li Yanyan, Lescop Ewen, Guittet Eric, Rebuffat Sylvie & Zirah Séverine, February 2012 — Sequence Determinants Governing the Topology and Biological Activity of a Lasso Peptide, Microcin J25. ChemBioChem. Vol. 13, n° 3, p. 371-380.
    ISSN: 
    14394227
    https://dx.doi.org/10.1002/cbic.201100702
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