Affiliation entity
CCE Cyanobacteria, Cyanotoxins and Environment
Interdisplinary research theme
Utilisation de méthodes d'ingénierie moléculaire et d'approche basée sur la modélisation pour concevoir, ingénierie, affinité et humaniser des anticorps
Researches
Accreditation to supervise research
Speciality
Biochimie / Immunologie / Toxicologie

Contact

E-mail
philippe.billiald [at] mnhn.fr
philippe.billiald [at] u-psud.fr
Phone
01 40 79 31 55
Address(es)

12 rue Buffon

75005 Paris

Teaching

  • Université Paris-Sud : Biochimie, Faculté de Pharmacie et Première Année Commune aux Etudes de Santé (Médecine, Pharmacie, Odontologie, Maïeutique)
  • Muséum : M2 parcours Toxines, microorganismes et Médiateurs chimiques dans les Ecosystèmes

Publications

2020
  • Karim-Silva Sabrina, Becker-Finco Alessandra, Jiacomini Isabella Gizzi, Boursin Fanny, Leroy Arnaud, Noiray Magali, de Moura Juliana, Aubrey Nicolas, Billiald Philippe & Alvarenga Larissa M., April 2020 — Loxoscelism: Advances and Challenges in the Design of Antibody Fragments with Therapeutic Potential. Envenoming due to Loxosceles spider bites still remains a neglected disease of particular medical concern in the Americas. To… Toxins vol. 12, n° 4, p. 256 Number: 4 Publisher: Multidisciplinary Digital Publishing Institute
    https://dx.doi.org/10.3390/toxins12040256
2019
  • Demeu Lara Maria Kalempa, Soares Rodrigo Jahn, Miranda Juliana Severo, Pacheco-Lugo Lisandro A., Oliveira Kelin Gonçalves, Plaza Cristian Andrés Cortez, Billiald Philippe, Moura Juliana Ferreira de, Yoshida Nobuko, Alvarenga Larissa Magalhães & DaRocha Wanderson Duarte, October 2019 — Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion. Trypanosoma cruzi is a flagellate protozoan pathogen that causes Chagas disease. Currently there is no preventive treatment and… PLOS ONE vol. 14, n° 10, e0223773
    ISSN
    1932-6203
    https://dx.doi.org/10.1371/journal.pone.0223773
2016
  • Karim-Silva Sabrina, Moura Juliana de, Noiray Magali, Minozzo Joao Carlos, Aubrey Nicolas, Alvarenga Larissa M. & Billiald Philippe, August 2016 — Generation of recombinant antibody fragments with toxin-neutralizing potential in loxoscelism. Loxosceles spider bites often lead to serious envenomings and no definite therapy has yet been established. In such a context,… Immunology Letters vol. 176, Supplement C, p. 90-96
    ISSN
    0165-2478
    https://dx.doi.org/10.1016/j.imlet.2016.05.019
  • Jiacomini Isabella, Silva Sabrina K., Aubrey Nicolas, Muzard Julien, Chavez-Olortegui Carlos, De Moura Juliana, Billiald Philippe & Alvarenga Larissa M., May 2016 — Immunodetection of the “brown” spider ( Loxosceles intermedia ) dermonecrotoxin with an scFv-alkaline phosphatase fusion protein. Immunology Letters vol. 173, , p. 1-6
    ISSN
    01652478
    https://dx.doi.org/10.1016/j.imlet.2016.03.001
  • Lakhrif Zineb, Pugnière Martine, Henriquet Corinne, di Tommaso Anne, Dimier-Poisson Isabelle, Billiald Philippe, Juste Matthieu O. & Aubrey Nicolas, February 2016 — A method to confer Protein L binding ability to any antibody fragment. mAbs vol. 8, n° 2, p. 379-388
    ISSN
    1942-0862, 1942-0870
    https://dx.doi.org/10.1080/19420862.2015.1116657
2014
  • Alvarenga Larissa, Zahid Muhammad, Tommaso Anne, Juste Matthieu, Aubrey Nicolas, Billiald Philippe & Muzard Julien, August 2014 — Engineering Venom’s Toxin-Neutralizing Antibody Fragments and Its Therapeutic Potential. Toxins vol. 6, n° 8, p. 2541-2567
    ISSN
    2072-6651
    https://dx.doi.org/10.3390/toxins6082541
  • Alvarenga Larissa M., Muzard Julien, Ledreux Aurélie, Bernard Cécile & Billiald Philippe, April 2014 — Colorimetric engineered immunoprobe for the detection and quantification of microcystins. Journal of Immunological Methods vol. 406, , p. 124-130
    ISSN
    00221759
    https://dx.doi.org/10.1016/j.jim.2014.02.014
2013
  • Fields Conor, O’Connell David, Xiao Sujing, Lee Gil U., Billiald Philippe & Muzard Julien, June 2013 — Creation of recombinant antigen-binding molecules derived from hybridomas secreting specific antibodies. This protocol describes the design and development of recombinant monovalent antigen-binding molecules derived from monoclonal… Nature Protocols vol. 8, n° 6, p. 1125-1148
    ISSN
    1754-2189
    https://dx.doi.org/10.1038/nprot.2013.057
2012
  • Zahid M., Mangin P., Loyau S., Hechler B., Billiald P., Gachet C. & Jandrot-Perrus M., December 2012 — The future of glycoprotein VI as an antithrombotic target. Summary.  The treatment of acute coronary syndromes has been considerably improved in recent years with the introduction of… Journal of Thrombosis and Haemostasis vol. 10, n° 12, p. 2418-2427
    ISSN
    1538-7836
    https://dx.doi.org/10.1111/jth.12009
  • di Tommaso Anne, Juste Matthieu O., Martin-Eauclaire Marie-France, Dimier-Poisson Isabelle, Billiald Philippe & Aubrey Nicolas, April 2012 — Diabody Mixture Providing Full Protection against Experimental Scorpion Envenoming with Crude Androctonus australis Venom. Journal of Biological Chemistry vol. 287, n° 17, p. 14149-14156
    ISSN
    0021-9258, 1083-351X
    https://dx.doi.org/10.1074/jbc.M112.348912
See all publications