I am interested in male gametogenesis of Plasmodium and more specifically in the formation and assembly of the flagellum of male gametes. By an appraoch combing functional genomics to cell biology, I aim to identify and characterise key actors in this essential step of the parasite life cycle. My model organism is the parasite Plasmodium berghei , the rodent model.
Spelman Kevin, Depoix Delphine, McCray Megan, Mouray Elisabeth & Grellier Philippe, July 2011 — The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo antimalarial activity.Phytother Res.Vol. 25, n° 7, p. 1098-1101.